Medecox Oral Solution

MEDECOX Oral Powder/Vip is a light white homogeneous powder containing 10 mg Decoquinate in each gr.

PHARMACOLOGICAL PROPERTIES

The Decoquinate in MEDECOX Oral Powder/Vip  is a substance obtained by the chemical synthesis of 4-hydroxyquinoline, an antiprotozoal substance within the quinolone group. It exerts its effect by inhibiting electron transfer in the mitochondrial cytochrome system of parasites. It affects the sporozoite stage in coccidia. Although the parasites enter the host cell, they cannot continue their subsequent development due to the effect of the drug. By stopping the development of Eimeria sp and Toxoplasma sp. parasites present in the early developmental stages in the small intestine, it prevents the clinical appearance of the disease.
Decoquinate is rapidly absorbed and passes rapidly through the gastrointestinal region, being excreted unchanged in the feces. Almost the entire administered dose is excreted by this route. In cattle, the rate of excretion via the urinary tract is quite low. Decoquinate is excreted in cattle without being extensively metabolized, and the main component is found in edible tissues and feces. No sex-related variation is observed in terms of the route and rate of absorption, distribution and excretion.
When the excretion kinetics in calves and lambs are compared, it has been observed that it is excreted in sheep at the same rate as in cattle or slightly faster.

INDICATIONS

MEDECOX Oral Powder/VIP is used in lambs and calves to treat and control Coccidiosis. In addition, it is used by adding it to the feed of animals to prevent perinatal losses and abortions caused by Toxoplasmosis in ewes. It can also be used in pregnant ewes.

USAGE AND DOSAGE

“Unless otherwise recommended by the veterinarian.”
For the prevention of coccidiosis in calves: The pharmacological dose is 0,5 mg/ kg.bw./day.
It is mixed into the daily feed that the animals will consume and given for 28 days. If there is a risk of disease, treatment is continued.
For the treatment of coccidiosis in calves: The pharmacologicaldose is 1 mg /kg. bw./ day.
It is mixed into the daily feed that the animals will consume and given for 28 days.
Use in pregnant ewes for the purpose of preventing coccidiosis in lambs:
The pharmacological dose is 0,5 mg /kg. bw./ day.
It is mixed into the feed that the animals will consume and given for 28 days. If there is a risk of disease, treatment is continued.
For the purpose of treating coccidiosis in lambs: The pharmacologicaldose is 1 mg /kg. bw./ day.
It is mixed into the feed that the animals will consume and given for 28 days.
To prevent perinatal losses and abortions caused by Toxoplasmosis in sheep: The pharmacological dose is 2 mg/kg.bw./day.
It is mixed into the daily feed that the animals will consume. The drug should be started 14 weeks before lambing and used continuously.
Preparation of the medicated feed:
To ensure an even distribution, for each 1 unit of MEDECOX Oral Powder/Vip in the amount to be used, it should be premixed with 6 units of feed. The feed should be prepared daily.

PACKAGE

It is offered for sale in 20 gr white plastic bottles as boxed, and in 500 gr, 1 kg, 2.5 kg and 5 kg white plastic jars